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Figure 2 | Journal of Hematology & Oncology

Figure 2

From: A novel vaccine for mantle cell lymphoma based on targeting cyclin D1 to dendritic cells via CD40

Figure 2

Long live of specific T cells to cyclin D1. (A) Another blood draw 3 months later from the MCL patient ACC-­2000, indicated as ACC-­2003. IFN-­γ cytokine secretion and percentage of CD4+IFN-γ+ and CD8+IFN-γ+ population from IFN-γ intracellular staining were shown. MAD is considered a positive cutting line (shown as a red dash line). (B) The potential cyclin D1 epitopes that stimulate CD4+T cells to produce IFN-­γ based on intracellular staining data are indicated on the protein sequence of cyclin D1. Data shown are two independent experiments by using PBMCs from two blood draws of the same MCL patient.

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