Figure 2
Eltrombopag does not enhance proliferation of human myeloma cell lines. (A) KMS-11 or (B) OCI-My5 cells were incubated with varying concentrations of eltrombopag in the presence or absence of G-CSF (10 ng/ml) and EPO (3 U/ml) for 6 days and cell viability determined by measuring fluorescence signals at 535Ex/595Em using the CellTiter Blue Assay. Data are presented as mean ± S.D. of triplicate experiments. *p < 0.02. ELT = eltrombopag; TPO = thrombopoietin; CTRL = control.