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Table 2 GAS5 increases the sensitivity of A549 to gefitinib

From: The long non-coding RNA, GAS5, enhances gefitinib-induced cell death in innate EGFR tyrosine kinase inhibitor-resistant lung adenocarcinoma cells with wide-type EGFR via downregulation of the IGF-1R expression

Cell line

IC 50

IC 50

Ratio

Gefitinib

Gefitinib + GAS5

A549

46.40 μM

3.665 μM

12.66

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Journal of Hematology & Oncology

ISSN: 1756-8722

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