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Table 1 Clinical patient characteristics and their association with survival outcomes

From: The serum CXCL13 level is associated with the Glasgow Prognostic Score in extranodal NK/T-cell lymphoma patients

    

PFS

 

OS

 

Characteristics

 

n

%

HR

P

HR

P

Age (years)

≤60

56

81

    
 

>60

13

19

2.164

0.039

2.489

0.024

Sex

Male

46

33

    
 

Female

23

67

1.215

0.575

0.752

0.494

Performance status

ECOG 0/1

56

81

    
 

ECOG ≥2

13

19

4.372

<0.001

3.736

0.001

Ann Arbor stage

I/II

29/11

42/16

    
 

III/IV

5/24

7/35

1.935

<0.001

1.898

<0.001

Serum LD

Normal

30

44

    
 

Increased

39

56

3.124

0.002

2.456

0.026

B symptoms

Absence

39

56

    
 

Presence

30

44

2.634

0.004

2.310

0.027

LN involvement

Absence

40

58

    
 

Presence

29

42

2.236

0.017

3.258

0.002

Primary site

Nasal

41

59

    
 

Extranasal

28

41

4.092

<0.001

4.240

<0.001

Bone marrow invasion

No

56

81

    
 

Yes

13

19

6.591

<0.001

5.298

<0.001

Extranodal involvement

0/1

43

62

    
 

≥2

26

38

2.948

0.001

2.616

0.011

EBV DNA

Non-detectable

42

61

    
 

Detectable

27

39

4.111

<0.001

3.482

<0.001

IPI

Low/low-intermediate

33/11

48/16

    
 

High-intermediate/High

17/8

24/12

2.482

<0.001

2.031

<0.001

NKPI

Group I/II

18/8

26/12

    
 

Group III/IV

20/23

29/33

2.162

<0.001

2.036

0.001

GPS

0

32

46

    
 

1

22

32

    
 

2

15

22

2.660

<0.001

3.052

<0.001

  1. Abbreviations: PFS progression-free survival, OS overall survival, HR hazard ratio, ECOG Eastern Cooperative Oncology Group, LD lactate dehydrogenase, LN lymph node, EBV Epstein-Barr virus, IPI International Prognostic Index, NKPI NK/T-cell Lymphoma Prognostic Index, CRP C-reactive protein, GPS Glasgow Prognostic Score.
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Journal of Hematology & Oncology

ISSN: 1756-8722

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