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Table 2 The association of CXCL13 and CCL3 with unfavorable parameters

From: The serum CXCL13 level is associated with the Glasgow Prognostic Score in extranodal NK/T-cell lymphoma patients

  

CXCL13

  

GPS

  

Characteristics

 

Low

High

P

0/1

2

P

Age (years)

≤60

32

24

 

48

8

 
 

>60

3

10

0.034

6

7

0.005

Ann Arbor stage

I/II

30

10

 

37

3

 
 

III/IV

5

24

<0.001

17

12

0.001

Serum LDH

Normal

22

8

 

28

2

 
 

Increased

13

26

0.001

26

13

0.009

B symptoms

Absence

25

14

 

35

4

 
 

Presence

10

20

0.015

19

11

0.017

LN involvement

Absence

25

15

 

36

4

 
 

Presence

10

19

0.029

18

11

0.008

Primary site

Nasal

29

12

 

38

3

 
 

Extranasal

6

22

<0.001

16

12

0.001

Bone marrow invasion

No

33

23

 

49

7

 
 

Yes

2

11

0.006

5

8

0.001

Extranodal involvement

0/1

29

14

 

38

5

 
 

≥2

6

20

<0.001

16

10

0.015

EBV DNA

Non-detectable

29

13

 

38

4

 
 

Detectable

6

21

<0.001

16

11

0.006

IPI

L/LI

30

14

 

42

2

 
 

HI/H

5

20

<0.001

12

13

<0.001

NKPI

Group I/II

22

4

 

24

2

 
 

Group III/IV

13

30

<0.001

30

13

0.036

  1. Abbreviations: LDH lactate dehydrogenase, LN lymph node, EBV Epstein-Barr virus, IPI International Prognostic Index, NKPI NK/T-cell Lymphoma Prognostic Index, GPS Glasgow Prognostic Score.