Diseases and disorders | Species | F-BAR protein changes | PMID ID# |
---|---|---|---|
Developmental and vascular disorders | |||
Embryonic defects | Drosophila, zebrafish | CIP4↑, PACSIN3↓ | 23424199, 19997509 |
Dorsoventral defects | Zebrafish | FCHO1↓ | 22484487 |
Vascular defects | Zebrafish | NOSTRIN↓ | 22751148 |
Postnatal retinal angiogenisis | Mice | NOSTRIN↓ | 22751148 |
Neurological disorders | |||
Neurodevelopmental disorders | Mice | srGAP2↓, srGAP3↓ | 23505444, 22820399 |
3p syndrome | Human | srGAP3 deletion | 19760623 |
Huntington’s disease | Human | CIP4↑, PACSIN1↓ | 12604778, 23852340 |
Epileptic seizures | Mice | PACSIN1↓ | 21926968 |
Autoinflammatory diseases | |||
Wiskott-Aldrich syndrome | Human | FBP17↓ | 19155218 |
PAPA syndrome | Human | PSTPIP1 mutation | 21532836 |
Chronic multifocal osteomyelitis | Mice | PSTPIP2 mutation | 16122996 |
Cancers | |||
Bladder tumor | Human | FBP17↑ | 21421245 |
Breast tumor | Human | CIP4↓ | 21525036 |
Leukemia | Human | FBP17↑, FES/FER↑, FCHSD2↑ | 11438682, 22201778, 22902056 |
Cardiac hypertrophy | Rat | CIP4↑ | 23915320 |
Glucose uptake elevation | Rat, mice | CIP4↓, PACSIN3↑ | 19509061, 17320047 |
Renal dysfunction | Human | CIP4↑ | 22745576 |