Table 1 Clinical characteristics of all patients and stratified by D5 peripheral blast clearance rate (D5-PBCR)

Age, y, median (range)

44.5 (14–74)

44 (15–67)

45 (14–74)

0.467

0.996

 Male

61

24

37

 Female

35

13

20

WBC count (×10⁹/L), median (range)

13.3 (1.32–249.90)

26.99 (3.2–120.9)

9.20 (1.32–249.90)

0.160

Hemoglobin (g/L), median (range)

85.0 (34.90–136.00)

89.5 (55.0–136.0)

82.0 (34.9–125.0)

0.051

Platelet (×10⁹/L), median (range)

38.0 (3.00–455.00)

38.5 (6.0–179.0)

36.0 (3.0–221.0)

0.975

Blasts in bone marrow (%), median (range)

65.0 (14.50–98.00)

71.0 (21.5–96)

60.1 (14.5–98.0)

0.038

Blasts in peripheral blood (/μL), median (range)

3730.7 (11.32–246,000)

4961.7 (479.9–124,900)

3730.7 (11.32–246,000)

0.035

0.229

 M1

2

1

1

 M2

24

5

18

 M4

43

19

24

 M4Eo

2

2

0

 M5

19

7

11

 M6

1

1

0

 NA

5

2

3

0.045

 Favorable

23

12

11

0.148

 Intermediate

53

22

30

0.515

 Unfavorable

20

3

16

0.019

-

Cross-lineage antigen expression

63

29

34

Asynchronous antigen expression

6

0

6

Antigen dim/strong expression

13

6

6

Antigen expression missing

8

4

3

CR (%)

67 (69.79)

35 (94.6)

32 (56.1)

<0.001

MRD (+) (%)^b

29 (55.77)

14 (50)

15 (62.5)

0.366

Relapse (%)

26 (32.50)

7 (19.44)

18 (42.86)

0.027