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Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: HER2/neu-directed therapy for biliary tract cancer

Fig. 1

A 61-year-old female with gallbladder carcinoma invading the liver. Axial contrast-enhanced CT images demonstrate a a 2.4 × 1.3 cm polypoid mass (small arrowheads) in the gallbladder neck causing gallbladder obstruction. The mass directly invades the liver, with a 2.9 × 3.9 cm liver mass (arrow). b After 3 months of trastuzumab and FOLFOX, the polypoid gallbladder mass is no longer visualized, and the liver mass decreased to 1.2 × 1.1 cm (arrow). The patient was then treated with en bloc cholecystectomy and extended right hepatectomy, followed by capecitabine and trastuzumab for 7 months. c After 6 months of observation (14 months after surgery), the patient had small volume recurrence to retroperitoneal lymph nodes (large arrowheads). After treatment with FOXFOX and trastuzumab for 3 months, d a previously seen 1-cm retroperitoneal lymph node is nearly imperceptible

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