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Fig. 4 | Journal of Hematology & Oncology

Fig. 4

From: Knockdown of SUMO-activating enzyme subunit 2 (SAE2) suppresses cancer malignancy and enhances chemotherapy sensitivity in small cell lung cancer

Fig. 4

SAE2 is essential for the migratory and invasive potential of SCLC cells in vitro. a Transwell invasion and migration assays of shCtrl-H446 and shSEA2 H446 tumor cells were performed. b The results are showed as an average of the number of migration/invasion cells from six random microscopic fields. c MMP2 and MMP9 protein level was measured by Western blot. Each data point represents mean ± SD of three independent experiments (***P < 0.001)

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