Identification of the NUP98-PHF23 fusion gene in pediatric cytogenetically normal acute myeloid leukemia by whole-transcriptome sequencing

Table 1 Clinical features of pediatric CN-AML patients harboring the NUP98-PHF23 fusion gene

Id	Age, years	Gender	WBC, x 10⁹/L	FAB	BM blast, % at diagnosis	Extramedullary involvement	HSCT (type)	CR after induction therapy	Relapse (site)	Disease-free duration (months)	Survival duration (months)
CN-AML_54^a	2.9	M	187	M1	90	No	Yes (AUTO)	Yes	Yes (BM)	5	30^b
CN-AML_66^a	9.0	M	1.2	M0	70	No	Yes (MUD)	Yes	–	65	66
CN-AML_3	9.7	M	6.9	M4	40	No	Yes (MUD)	Yes	–	40	41
CN-AML_4	7.0	M	1.8	M5A	54	No	Yes (AUTO)	Yes	–	103	104

AUTO autologous, CR complete remission, HSCT hematopoietic stem cell transplantation, MUD matched unrelated donor, BM bone marrow, WBC white blood cells
^apatients identified by RNA-seq
^bdead patient

ISSN: 1756-8722