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Table 4 Initial therapy used to treat symptomatic patients diagnosed with Waldenström macroglobulinemia (WM) with only bone marrow involvement (BMWM) and those with extramedullary involvement (EMWM)

From: Waldenström macroglobulinemia with extramedullary involvement at initial diagnosis portends a poorer prognosis

Type of therapy

EMWM (n = 106)

BMWM (n = 206)

n (%)

n (%)

Treated for WM

  

 Yes

94 (88.67)

146 (70.87)

 Observation only

8 (7.55)

44 (21.36)

 Alternative medicine

2 (1.89)

9 (4.37)

 Missing data

2 (1.89)

7 (3.40)

Initial treatment

  

 Chemotherapy

20 (18.87)

23 (11.17)

 Targeted therapy

25 (23.58)

79 (38.35)

 Combination

49 (46.23)

44 (21.36)

Initial treatment with R

  

 Yes

72 (67.92)

118 (57.28)

 No

22 (20.75)

28 (13.59)

Initial treatment with NA

  

 Yes

35 (33.02)

61 (29.61)

 No

59 (55.67)

85 (41.26)

  1. R rituximab, NA nucleoside analogs