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Table 2 Univariate analysis for overall survival (OS) and progression-free survival (PFS)

From: Infused autograft lymphocyte-to-monocyte ratio and survival in T-cell lymphoma post-autologous peripheral blood hematopoietic stem cell transplantation

Variable OS PFS
  HR 95 % CI p HR 95 % CI p
Age > 60 years 1.532 0.784–2.900 0.2 1.400 0.789–2.422 0.2
Female versus male 1.153 0.606–2.170 0.7 1.359 0.787–2.342 0.3
B symptoms 1.919 1.094–3.615 0.05 1.425 0.790–2.485 0.2
Bulky disease 1.007 0.164–3.294 0.9 1.109 0.270–3.024 0.9
Hemoglobin < 12.0 g/dl 1.636 0.862–3.072 0.1 1.858 1.076–3.193 0.03
Platelet < 150 × 109/l 2.566 1.312–4.862 0.007 2.890 1.671–5.047 <0.001
Extra-nodal sites > 1 3.043 1.354–6.197 0.009 2.332 1.104–4.470 0.03
LDH (U/L) 6.695 3.001–17.77 <0.001 4.510 2.440–8.989 <0.001
Performance status > 1 1.788 0.674–3.972 0.2 2.033 0.885–4.089 0.09
Stage III/IV 3.817 1.630–11.160 <0.001 2.571 1.393–5.431 0.004
IPI > 2 4.442 2.342–8.459 <0.001 3.734 2.146–6.444 <0.001
Positive bone marrow 1.670 0.856–3.153 0.1 1.294 0.709–2.271 0.4
Infused CD34 0.893 0.758–1.032 0.1 0.950 0.832–1.070 0.4
CR prior to APHSCT 0.164 0.081–0.314 <0.001 0.186 0.106–0.321 <0.001
A-ALC ≥ 0.5 × 109/kg 0.358 0.188–0.676 0.002 0.294 0.167–0.511 <0.001
A-AMC ≥ 0.6 × 109/kg 3.207 1.585–7.175 <0.001 2.254 1.285–4.116 0.004
A-LMR ≥ 1 0.155 0.066–0.322 <0.001 0.196 0.104–0.353 <0.001
ALC-15 ≥ 0.5 cells/μl 0.158 0.072–0.304 <0.001 0.246 0.139–0.430 <0.001
AMC-15 ≥ 0.5 cells/μl 3.909 1.881–9.160 <0.001 2.645 1.489–4.918 <0.001
LMR-15 0.143 0.061–0.497 <0.001 0.214 0.116–0.378 <0.001
Plerixafor 0.954 0.497–1.925 0.7 0.886 0.510–1.587 0.8
  1. Abbreviations: A-ALC autograft absolute lymphocyte count, ALC-15 day 15 absolute lymphocyte count post-autologous peripheral hematopoietic stem cell transplantation, A-AMC autograft absolute monocyte count, AMC-15 day 15 absolute monocyte count post-autologous peripheral hematopoietic stem cell transplantation, A-LMR autograft lymphocyte/monocyte ratio, LMR-15 day 15 lymphocyte/monocyte ratio post-autologous peripheral hematopoietic stem cell transplantation, CR complete response, IPI International Prognostic Index, LDH lactate dehydrogenase