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Table 2 Univariate analysis for overall survival (OS) and progression-free survival (PFS)

From: Infused autograft lymphocyte-to-monocyte ratio and survival in T-cell lymphoma post-autologous peripheral blood hematopoietic stem cell transplantation

Variable

OS

PFS

 

HR

95 % CI

p

HR

95 % CI

p

Age > 60 years

1.532

0.784–2.900

0.2

1.400

0.789–2.422

0.2

Female versus male

1.153

0.606–2.170

0.7

1.359

0.787–2.342

0.3

B symptoms

1.919

1.094–3.615

0.05

1.425

0.790–2.485

0.2

Bulky disease

1.007

0.164–3.294

0.9

1.109

0.270–3.024

0.9

Hemoglobin < 12.0 g/dl

1.636

0.862–3.072

0.1

1.858

1.076–3.193

0.03

Platelet < 150 × 109/l

2.566

1.312–4.862

0.007

2.890

1.671–5.047

<0.001

Extra-nodal sites > 1

3.043

1.354–6.197

0.009

2.332

1.104–4.470

0.03

LDH (U/L)

6.695

3.001–17.77

<0.001

4.510

2.440–8.989

<0.001

Performance status > 1

1.788

0.674–3.972

0.2

2.033

0.885–4.089

0.09

Stage III/IV

3.817

1.630–11.160

<0.001

2.571

1.393–5.431

0.004

IPI > 2

4.442

2.342–8.459

<0.001

3.734

2.146–6.444

<0.001

Positive bone marrow

1.670

0.856–3.153

0.1

1.294

0.709–2.271

0.4

Infused CD34

0.893

0.758–1.032

0.1

0.950

0.832–1.070

0.4

CR prior to APHSCT

0.164

0.081–0.314

<0.001

0.186

0.106–0.321

<0.001

A-ALC ≥ 0.5 × 109/kg

0.358

0.188–0.676

0.002

0.294

0.167–0.511

<0.001

A-AMC ≥ 0.6 × 109/kg

3.207

1.585–7.175

<0.001

2.254

1.285–4.116

0.004

A-LMR ≥ 1

0.155

0.066–0.322

<0.001

0.196

0.104–0.353

<0.001

ALC-15 ≥ 0.5 cells/μl

0.158

0.072–0.304

<0.001

0.246

0.139–0.430

<0.001

AMC-15 ≥ 0.5 cells/μl

3.909

1.881–9.160

<0.001

2.645

1.489–4.918

<0.001

LMR-15

0.143

0.061–0.497

<0.001

0.214

0.116–0.378

<0.001

Plerixafor

0.954

0.497–1.925

0.7

0.886

0.510–1.587

0.8

  1. Abbreviations: A-ALC autograft absolute lymphocyte count, ALC-15 day 15 absolute lymphocyte count post-autologous peripheral hematopoietic stem cell transplantation, A-AMC autograft absolute monocyte count, AMC-15 day 15 absolute monocyte count post-autologous peripheral hematopoietic stem cell transplantation, A-LMR autograft lymphocyte/monocyte ratio, LMR-15 day 15 lymphocyte/monocyte ratio post-autologous peripheral hematopoietic stem cell transplantation, CR complete response, IPI International Prognostic Index, LDH lactate dehydrogenase
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Journal of Hematology & Oncology

ISSN: 1756-8722

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