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Table 1 IC50 values of bosutinib and imatinib calculated in the proliferation assay for K562S, K562DOX, and K562DOX/sh P-GP

From: In vitro and in vivo identification of ABCB1 as an efflux transporter of bosutinib

  K562S K562DOX K562DOX/sh P-GP
Bosutinib 6.5 nM 36.1 nM 3 nM
Imatinib 49.3 nM 234.1 nM 28 nM