Table 1 IC50 values of bosutinib and imatinib calculated in the proliferation assay for K562S, K562DOX, and K562DOX/sh P-GP
From: In vitro and in vivo identification of ABCB1 as an efflux transporter of bosutinib
| Â | K562S | K562DOX | K562DOX/sh P-GP |
|---|---|---|---|
Bosutinib | 6.5 nM | 36.1 nM | 3 nM |
Imatinib | 49.3 nM | 234.1 nM | 28 nM |