| |
HR
|
95 % CI
|
P value
|
|---|
|
Primary graft failure
| | | |
|
DSA
| | | |
|
MFI ≥ 10,000
|
1
| | |
|
2000 ≤ MFI < 10,000
|
0.940
|
0.284–3.177
|
0.919
|
|
MFI < 2000
|
0.187
|
0.048–0.730
|
0.016
|
|
OS
| | | |
|
Disease status
|
2.839
|
1.702–4.736
|
0.000
|
|
Primary graft failure
| | | |
|
GR
|
1
| | |
|
PGF
|
0.271
|
0.074–1.000
|
0.050
|
|
No primary graft failure
|
0.068
|
0.020–0.229
|
0.000
|
|
DFS
| | | |
|
Disease status
|
3.593
|
2.212–5.836
|
0.000
|
|
PGF
|
3.125
|
1.564–6.244
|
0.000
|
|
GR
|
1
| | |
|
PGF
|
0.284
|
0.077–1.044
|
0.058
|
|
No primary graft failure
|
0.084
|
0.025–0.279
|
0.000
|
|
Relapse
| | | |
|
Disease status
|
9.906
|
4.099–23.940
|
0.000
|
|
TRM
| | | |
|
PGF
| | | |
|
GR
|
1
| | |
|
PGF
|
0.209
|
0.056–0.790
|
0.021
|
|
No primary graft failure
|
0.031
|
0.0009–0.107
|
0.000
|
|
ANC
| | | |
|
CD34
|
1.370
|
1.106–1.697
|
0.004
|
|
PLT
| | | |
|
CD34
|
1.483
|
1.187–1.852
|
0.001
|
|
DSA
| | | |
|
MFI ≥ 10,000
|
1
| | |
|
2000 ≤ MFI < 10,000
|
3.074
|
1.137–8.311
|
0.027
|
|
MFI < 2000
|
3.301
|
1.358–8.022
|
0.008
|
-
Abbreviations: HR hazard ratio, CI confidence interval, DSAs donor-specific antibodies, MFI median fluorescence intensity, OS overall survival, GR graft rejection, PGF poor graft function, DFS disease-free survival, TRM transplant-related mortality, ANC absolute neutrophil count, PLT platelet
