Characteristic | HLA-matched HSCT | Haploidentical HSCT | P |
---|---|---|---|
(n = 35) | (n = 47) | ||
Age, years, median (range) | 35(5–52) | 35(8–50) | 0.679 |
Males/females, n | 22/13 | 24/23 | 0.287 |
WBC count at diagnose × 109, median (range) | 45.0(1.4–199.2) | 36.3 (1.6–274.4) | 0.147 |
CNS involvement | Â | Â | Â |
Yes/no | 3/32 | 6/41 | 0.548 |
Disease status at transplantation | Â | Â | Â |
CR1 | 26 | 37 | 0.584 |
>CR1 | 9 | 10 | Â |
BCR-ABL at transplantation | Â | Â | Â |
Negative/positive | 28/7 | 37/10 | 0.888 |
Average mos. from diagnosis to transplant (range) | 9.0(3–47) | 7.0(2–19) | 0.104 |
Cycles of prior chemotherapy (range) | 5.3(2–22) | 4.6(2–13) | 0.411 |
ABO match, no. (%) | Â | Â | 0.224 |
Matched | 12 | 27 | Â |
Minor mismatched | 8 | 7 | Â |
Major mismatched | 11 | 9 | Â |
Major and minor mismatched | 4 | 4 | Â |
Donor-recipient sex match | Â | Â | 0.323 |
Male-male | 10 | 16 | Â |
Male-female | 9 | 18 | Â |
Female-male | 12 | 8 | Â |
Female-female | 4 | 5 | Â |