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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: T cells are functionally not impaired in AML: increased PD-1 expression is only seen at time of relapse and correlates with a shift towards the memory T cell compartment

Fig. 2

Increased PD-1 expression on peripheral blood T cells of AML patients at relapse after allogeneic SCT compared to diagnosis. Expression of CD244 (a, e), PD-1 (b, f), CD160 (c, g), and TIM-3 (d, j) was measured on peripheral blood CD8+ (ad) and CD4+ (eh) T cells of 8 patients with an AML relapse after intensive chemotherapy (AML_rel) and 6 patients with an AML relapse after allogeneic SCT (AML_rel_allo) in comparison to 16 AML patients at diagnosis (AML_diag), and percentages of positive cells were depicted. Patient selection was limited to the age cohort >40 years. Statistical differences were calculated to AML_diag. *p ≤ 0.05; ****p ≤ 0.0001

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