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Fig. 4 | Journal of Hematology & Oncology

Fig. 4

From: T cells are functionally not impaired in AML: increased PD-1 expression is only seen at time of relapse and correlates with a shift towards the memory T cell compartment

Fig. 4

Skewing of T cells towards differentiated effector subtype in AML patients at relapse. Expression of CD45RA and CCR7 was measured on peripheral blood CD8+ (a, b) and CD4+ (c, d) T cells of 19 AML patients at diagnosis (AML_diag), 9 patients with an AML relapse after intensive chemotherapy (AML_rel), and 7 patients with an AML relapse after allogeneic SCT (AML_rel_allo) in comparison to 21 healthy controls (HC) and 8 HIV patients (HIV), and percentages of naïve (Tnaive; CD45RA+/CCR7+) and effector memory (Tem; CD45RA/CCR7) CD8+ and CD4+ T cells were plotted as a variable of age. Linear regression between T cell subset percentages and age was calculated and depicted

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