Fig. 6

Sal-YB1 could trigger the caspase-dependent apoptosis signalling pathway. a YB1-treated mouse tumor tissues showed high expression of caspase 3 by flow cytometry. Gray filled histogram and continuous line represented the YB1-untreated and -treated mice, respectively. b–f Cleaved caspase 1, 3, 8, and 9 and TSG6 could be increased in Sal-YB1-treated tumor tissues by Western blot. g Western bands. The error bars showed means ± SEM for three nude mice in each group. *P < 0.05 and ^*** P < 0.001 by an unpaired two-tailed t test