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Table 4 Causes of NRM

From: Clinical significance of high-dose cytarabine added to cyclophosphamide/total-body irradiation in bone marrow or peripheral blood stem cell transplantation for myeloid malignancy

Cause of NRM

Total

CY/TBI

HDCA/CY/TBI

 

N

%

N

%

N

%

p

Infection

110

27.3

78

26.4

32

29.6

0.52

 Bacteria

61

 

43

 

18

  

 Virus

19

 

14

 

5

  

 Fungi

13

 

9

 

4

  

Rejection/engraftment failure

3

0.7

3

1.0

0

0.0

0.29

TMA

10

2.5

8

2.7

2

1.9

0.62

VOD

15

3.7

12

4.1

3

2.8

0.54

GVHD

44

10.9

32

10.8

12

11.1

0.94

 Acute

20

 

14

 

6

  

 Chronic

24

 

18

 

6

  

Hemorrhage

24

6.0

18

6.1

6

5.6

0.84

Organ failure

127

31.5

95

32.2

32

29.6

0.62

 Liver

9

 

7

 

2

  

 Heart

13

 

8

 

5

  

 Kidney

6

 

4

 

2

  

 CNS

8

 

6

 

2

  

 Lung

82

 

62

 

20

  

  Interstitial pneumonia

40

 

29

 

11

  

  ARDS

14

 

13

 

1

  

Secondary malignancy

1

0.2

1

0.3

0

0.0

0.54

Others

69

17.1

48

16.3

21

19.4

 

Total

403

100.0

295

100.0

108

100.0

 
  1. Other abbreviations are explained in Tables 13
  2. TMA thrombotic microangiopathy, VOD veno-occlusive disease, CNS central nervous system, ARDS acute respiratory distress syndrome