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Fig. 7 | Journal of Hematology & Oncology

Fig. 7

From: NLK functions to maintain proliferation and stemness of NSCLC and is a target of metformin

Fig. 7

Ectopic expression of NLK increased cell proliferation ability and metformin compromised the promoting activity of NLK. a Expression of NLK in H522 lung cancer cell line after pEGFP-N1-NLK plasmids transfection. bc MTS assay and cell cycle analysis showing increased cell growth in H522 cells transfected with NLK expression plasmids, and metformin treatment reversed the pro-proliferation activity of NLK. An empty vector served as control. All transfected cells were collected for the next experiments 48 h after transfection. *p < 0.05

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