Fig. 3From: In vitro and in vivo single-agent efficacy of checkpoint kinase inhibition in acute lymphoblastic leukemia a Western blot analysis in BV-173 and NALM-6 cell lines after exposure to increasing concentrations of PF-00477736 (0.05, 0.1, and 0.2 uM for BV-173 and 0.1, 0.5, and 1 uM for NALM-6) or DMSO 0.1 % (−). b Western blot analysis in BV-173 and NALM-6 cell lines after exposure to PF-00477736 (+) at the concentration closest the IC50 or DMSO 0.1 % (−) at 18, 24, 30, and 48 h. c Western blot analysis in all leukemia cell lines after exposure to PF-00477736 (+) at the concentration closest the IC50 or DMSO 0.1 %Back to article page