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Table 1 Immunohistochemical results

From: In vitro and in vivo single-agent efficacy of checkpoint kinase inhibition in acute lymphoblastic leukemia

Tumor type

Chk1

pChk1

Chk2

pChk2

Cdc25C

pCDc25C

γH2A.X

pos

(%)

pos

(%)

pos

(%)

pos

(%)

pos

(%)

Pos

(%)

pos

(%)

ALL

51/54

(94)

45/56

(80)

55/57

(96)

15/55

(27)

57/57

(100)

38/55

(70)

40/59

(68)

B-ALL

31/31

(100)

28/33

(85)

32/33

(97)

11/32

(33)

34/34

(100)

23/32

(72)

25/36

(69)

T-ALL

20/23

(87)

17/23

(74)

23/24

(96)

4/23

(17)

23/23

(100)

15/23

(65)

15/23

(65)

  1. pos number of positive cases/number of evaluable cases