Fig. 1
From: Small PARP inhibitor PJ-34 induces cell cycle arrest and apoptosis of adult T-cell leukemia cells
PJ-34 induces S/G2M cell cycle arrest. a Cell cycle analysis of HTLV-I-transformed and ATL cells after DMSO or PJ-34 treatment. b Cell cycle profile of DMSO- or PJ-34-treated cells. c Cell tracking of MT-2 with CFDA-SE after DMSO or PJ-34 treatment. Representative results are shown here. d Western blot of cyclin E, cyclin A, cyclin B1, and p21 in MT-2, MT-4, and C91PL cells after DMSO or 25 μM PJ-34 treatment. Actin was used to confirm equal loading