Fig. 3From: Small PARP inhibitor PJ-34 induces cell cycle arrest and apoptosis of adult T-cell leukemia cellsPJ-34 induces cell apoptosis in most HTLV-I-transformed and ATL cells except for C91PL and MT-2 cells. a HTLV-1-transformed and (b) ATL cells were treated with 25 μM PJ-34 for 3 days. Cells were subsequently stained for annexin V and PI and analyzed for apoptosis by FACS analysis. c MT-4 cell line was treated with DMSO or different amounts of PJ-34 (5, 10, 25 μM). Cells were subsequently stained for annexin V and PI and analyzed for apoptosis by FACS analysisBack to article page