Fig. 3From: Overexpression of the long non-coding RNA PVT1 is correlated with leukemic cell proliferation in acute promyelocytic leukemiaPVT1 inhibition attenuates the proliferation of APL cells. The PVT1 expression level was detected in NB4 cells transfected with siRNA specifically targeting PVT1 (si-PVT1) or negative control siRNA (si-NC). a qRT-PCR analysis showed that the PVT1 expression level in cells transfected with si-PVT1 was significantly lower than that in cells transfected with si-NC. b PVT1 knockdown impaired the growth of APL Cells. The data are the result of three independent experiments and are presented as means ± SD. c qRT-PCR and Western blot analysis of MYC in APL cells after siRNA transfectionBack to article page