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Fig. 4 | Journal of Hematology & Oncology

Fig. 4

From: MicroRNA-26a suppresses epithelial-mesenchymal transition in human hepatocellular carcinoma by repressing enhancer of zeste homolog 2

Fig. 4

The relationships between miR-26a expression and the expression of EZH2 and E-cadherin in human HCC tissue. a A HCC tissue microarray was used to analyze E-cadherin expression using immunohistochemistry. Representative images are shown (×200). b miR-26a was positively associated with intratumoral E-cadherin expression (R = 0.462, P = 0.001). c Patients with high miR-26a expression had significantly higher E-cadherin expression compared with those with low miR-26a expression (P = 0.003). d Representative images of EZH2 staining are shown (×200). e An inverse association between miR-26a and EZH2 expression were found (R = −0.472, P = 0.001). f Patients with high miR-26a expression had significantly lower EZH2 expression compared with those with low miR-26a expression (P = 0.004)

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