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Table 1 Associations between tissue SDF-1α expression and clinicopathologic characteristics of EC patients

From: Cancer-associated fibroblasts promote the progression of endometrial cancer via the SDF-1/CXCR4 axis

Variables SDF-1α expression (n (%)) Total N χ 2 P
Negative Low High
Age at diagnosis (years)
 <60 14 (11.2) 43 (34.4) 68 (54.4) 125 1.133 0.567
 ≥60 12 (15.6) 28 (36.4) 37 (48.0) 77
Menopausal status
 Yes 15 (10.6) 53 (37.6) 73 (51.8) 141 2.604 0.272
 No 11 (18.0) 18 (29.5) 32 (52.5) 61
Histologic subtype
 Endometrioid 22 (11.9) 66 (35.7) 97 (52.4) 185 1.616 0.446
 Nonendometrioid 4 (23.5) 5 (29.4) 8 (47.1) 17
Histopathologic grade
 G1 14 (14.4) 34 (35.1) 49 (50.5) 97 1.460 0.834
 G2 7 (9.2) 29 (38.2) 40 (52.6) 76
 G3 4 (13.8) 9 (31.0) 16 (55.2) 29
Myometrial invasion
 <1/2 16 (10.9) 60 (40.8) 71 (48.3) 147 7.998 0.018*
 ≥1/2 10 (18.2) 11 (20.0) 34 (61.8) 55
FIGO stage
 I–II 22 (13.2) 63 (37.7) 82 (49.1) 167 3.456 0.172
 III–IV 4 (11.4) 8 (22.9) 23 (65.7) 35
Lymph node metastasis
 Yes 1 (6.3) 2 (12.5) 13 (81.2) 16 6.530 0.038*
 No 24 (12.9) 70 (37.6) 92 (49.5) 186
  1. The data are presented as numbers of cases (percentages of cases)
  2. * indicates P < 0.05