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Table 1 Associations between tissue SDF-1α expression and clinicopathologic characteristics of EC patients

From: Cancer-associated fibroblasts promote the progression of endometrial cancer via the SDF-1/CXCR4 axis

Variables

SDF-1α expression (n (%))

Total N

χ 2

P

Negative

Low

High

Age at diagnosis (years)

 <60

14 (11.2)

43 (34.4)

68 (54.4)

125

1.133

0.567

 ≥60

12 (15.6)

28 (36.4)

37 (48.0)

77

Menopausal status

 Yes

15 (10.6)

53 (37.6)

73 (51.8)

141

2.604

0.272

 No

11 (18.0)

18 (29.5)

32 (52.5)

61

Histologic subtype

 Endometrioid

22 (11.9)

66 (35.7)

97 (52.4)

185

1.616

0.446

 Nonendometrioid

4 (23.5)

5 (29.4)

8 (47.1)

17

Histopathologic grade

 G1

14 (14.4)

34 (35.1)

49 (50.5)

97

1.460

0.834

 G2

7 (9.2)

29 (38.2)

40 (52.6)

76

 G3

4 (13.8)

9 (31.0)

16 (55.2)

29

Myometrial invasion

 <1/2

16 (10.9)

60 (40.8)

71 (48.3)

147

7.998

0.018*

 ≥1/2

10 (18.2)

11 (20.0)

34 (61.8)

55

FIGO stage

 I–II

22 (13.2)

63 (37.7)

82 (49.1)

167

3.456

0.172

 III–IV

4 (11.4)

8 (22.9)

23 (65.7)

35

Lymph node metastasis

 Yes

1 (6.3)

2 (12.5)

13 (81.2)

16

6.530

0.038*

 No

24 (12.9)

70 (37.6)

92 (49.5)

186

  1. The data are presented as numbers of cases (percentages of cases)
  2. * indicates P < 0.05