Fig. 6

a Venn diagrams of co-expressed and uniquely dysregulated genes compared to control FVB/N mice in the AML post MDS, _MRP8NRASD12 and _MRP8hBCL-2 transgenic mice; b Heat Map of GEP performed on the Sca1+ cells of AML post MDS mice (n = 3) compared to control FVB/N mice (n = 3); c Distribution in % of the significantly dysregulated genes in the KEGG DAVID annotation pathways; d Analysis of the differentially expressed (i.e., upregulated in the AML post MDS transgenic mice and downregulated in the founder mice and vice versa). Genes in regular font are expressed at lower levels and genes in bold font are expressed in higher levels. Examples of microarray data are shown for each intersection