Fig. 2From: Haplo-insufficiency of both BubR1 and SGO1 accelerates cellular senescence BubR1 +/− or SGO1 +/− deficiency leads to enhanced expression of β-galactosidase. Primary MEFs of various genetic backgrounds (wild-type, BubR1 +/−, SGO1 +/−, and BubR1 +/− SGO1 +/−) at passage 6 were stained for senescence-associated β-Gal activity (blue according to the manufacturer’s protocol. β-Gal-positive cells were stained with blueBack to article page