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Fig. 4 | Journal of Hematology & Oncology

Fig. 4

From: Allogeneic stem cell transplantation for X-linked agammaglobulinemia using reduced intensity conditioning as a model of the reconstitution of humoral immunity

Fig. 4

TRECs and KRECs as markers of T- and B-cell neogenesis. sjKRECs (dotted black), which serve as an indicator of B-cell neogenesis, became positive 16 days post-SCT, increased to 6300 copies/μg DNA at 42 days, and were maintained at a high level thereafter. cjKRECs (solid black), an indicator of B-cell numbers, fluctuated almost in parallel with sjKRECs. The recovery of TRECs (solid gray) was slow, but became detectable 1 year post-HSCT

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