Fig. 4
Metformin together with sorafenib suppressed recurrence and metastasis of HCC after surgical resection. a Recurrent tumor in different treatment groups. b The size (mm3) of tumors was determined. c Metastatic tumor nodules were detected by HE staining in lung(100×). d Average number of metastatic tumor nodules in lung. Error bars represent the standard deviation (*P < 0.05, **P < 0.01)