TY - JOUR AU - Koike, K. AU - Matsuda, K. PY - 2008 DA - 2008// TI - Recent advances in the pathogenesis and management of juvenile myelomonocytic leukemia JO - Br J Haematol VL - 141 UR - https://doi.org/10.1111/j.1365-2141.2008.07104.x DO - 10.1111/j.1365-2141.2008.07104.x ID - Koike2008 ER - TY - JOUR AU - Dvorak, C. C. AU - Loh, M. L. PY - 2014 DA - 2014// TI - Juvenile myelomonocytic leukemia: molecular pathogenesis informs current approaches to therapy and hematopoietic cell transplantation JO - Front Pediatr VL - 2 UR - https://doi.org/10.3389/fped.2014.00025 DO - 10.3389/fped.2014.00025 ID - Dvorak2014 ER - TY - JOUR AU - Sakaguchi, H. AU - Okuno, Y. AU - Muramatsu, H. AU - Yoshida, K. AU - Shiraishi, Y. AU - Takahashi, M. PY - 2013 DA - 2013// TI - Exome sequencing identifies secondary mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia JO - Nat Genet VL - 45 UR - https://doi.org/10.1038/ng.2698 DO - 10.1038/ng.2698 ID - Sakaguchi2013 ER - TY - JOUR AU - Matsuda, K. AU - Nakazawa, Y. AU - Iwashita, C. AU - Kurata, T. AU - Hirabayashi, K. AU - Saito, S. PY - 2014 DA - 2014// TI - Myeloid progenitors with PTPN11 and nonRAS pathway gene mutations are refractory to treatment with 6-mercaptopurine in juvenile myelomonocytic leukemia JO - Leukemia VL - 287 UR - https://doi.org/10.1038/leu.2014.58 DO - 10.1038/leu.2014.58 ID - Matsuda2014 ER - TY - JOUR AU - Stieglitz, E. AU - Troup, C. B. AU - Gelston, L. C. AU - Haliburton, J. AU - Chow, E. D. AU - Yu, K. B. PY - 2015 DA - 2015// TI - Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia JO - Blood VL - 125 UR - https://doi.org/10.1182/blood-2014-09-601690 DO - 10.1182/blood-2014-09-601690 ID - Stieglitz2015 ER - TY - JOUR AU - Caye, A. AU - Strullu, M. AU - Guidez, F. AU - Cassinat, B. AU - Gazal, S. AU - Fenneteau, O. PY - 2015 DA - 2015// TI - Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network JO - Nat Genet VL - 47 UR - https://doi.org/10.1038/ng.3420 DO - 10.1038/ng.3420 ID - Caye2015 ER - TY - JOUR AU - Locatelli, F. AU - Niemeyer, C. M. PY - 2015 DA - 2015// TI - How I treat juvenile myelomonocytic leukemia JO - Blood VL - 125 UR - https://doi.org/10.1182/blood-2014-08-550483 DO - 10.1182/blood-2014-08-550483 ID - Locatelli2015 ER - TY - JOUR AU - Worth, A. AU - Rao, K. AU - Webb, D. AU - Chessells, J. AU - Passmore, J. AU - Veys, P. PY - 2003 DA - 2003// TI - Successful treatment of juvenile myelomonocytic leukemia relapsing after stem cell transplantation using donor lymphocyte infusion JO - Blood VL - 101 UR - https://doi.org/10.1182/blood-2002-07-2011 DO - 10.1182/blood-2002-07-2011 ID - Worth2003 ER - TY - JOUR AU - Yoshimi, A. 1. AU - Bader, P. AU - Matthes-Martin, S. AU - Starý, J. AU - Sedlacek, P. AU - Duffner, U. PY - 2005 DA - 2005// TI - Donor leukocyte infusion after hematopoietic stem cell transplantation in patients with juvenile myelomonocytic leukemia JO - Leukemia VL - 19 UR - https://doi.org/10.1038/sj.leu.2403721 DO - 10.1038/sj.leu.2403721 ID - Yoshimi2005 ER - TY - JOUR AU - Nabarro, S. AU - Thrasher, A. J. AU - Kempski, H. AU - Amrolia, P. AU - Anderson, J. PY - 2003 DA - 2003// TI - Generation of immunostimulatory dendritic cells from the malignant clone in patients with juvenile myelomonocytic leukemia JO - Leukemia VL - 17 UR - https://doi.org/10.1038/sj.leu.2403059 DO - 10.1038/sj.leu.2403059 ID - Nabarro2003 ER - TY - JOUR AU - Hirano, N. AU - Butler, M. O. AU - Xia, Z. AU - Berezovskaya, A. AU - Murray, A. P. AU - Ansén, S. PY - 2006 DA - 2006// TI - Identification of an immunogenic CD8+ T-cell epitope derived from gamma-globin, a putative tumor-associated antigen for juvenile myelomonocytic leukemia JO - Blood VL - 108 UR - https://doi.org/10.1182/blood-2006-04-017566 DO - 10.1182/blood-2006-04-017566 ID - Hirano2006 ER - TY - JOUR AU - Davila, M. L. AU - Bouhassira, D. C. AU - Park, J. H. AU - Curran, K. J. AU - Smith, E. L. AU - Pegram, H. J. PY - 2014 DA - 2014// TI - Chimeric antigen receptors for the adoptive T cell therapy of hematologic malignancies JO - Int J Hematol VL - 99 UR - https://doi.org/10.1007/s12185-013-1479-5 DO - 10.1007/s12185-013-1479-5 ID - Davila2014 ER - TY - JOUR AU - Maude, S. L. AU - Frey, N. AU - Shaw, P. A. AU - Aplenc, R. AU - Barrett, D. M. AU - Bunin, N. J. PY - 2014 DA - 2014// TI - Chimeric antigen receptor T cells for sustained remissions in leukemia JO - N Engl J Med VL - 371 UR - https://doi.org/10.1056/NEJMoa1407222 DO - 10.1056/NEJMoa1407222 ID - Maude2014 ER - TY - JOUR AU - Lee, D. W. AU - Kochenderfer, J. N. AU - Stetler-Stevenson, M. AU - Cui, Y. K. AU - Delbrook, C. AU - Feldman, S. A. PY - 2015 DA - 2015// TI - T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukemia in children and young adults: a phase 1 dose-escalation trial JO - Lancet VL - 385 UR - https://doi.org/10.1016/S0140-6736(14)61403-3 DO - 10.1016/S0140-6736(14)61403-3 ID - Lee2015 ER - TY - JOUR AU - Saito, S. AU - Nakazawa, Y. AU - Sueki, A. AU - Matsuda, K. AU - Tanaka, M. AU - Yanagisawa, R. PY - 2014 DA - 2014// TI - Anti-leukemic potency of piggyBac-mediated CD19-specific T cells against refractory Philadelphia chromosome-positive acute lymphoblastic leukemia JO - Cytotherapy VL - 16 UR - https://doi.org/10.1016/j.jcyt.2014.05.022 DO - 10.1016/j.jcyt.2014.05.022 ID - Saito2014 ER - TY - JOUR AU - Huye, L. E. AU - Nakazawa, Y. AU - Patel, M. P. AU - Yvon, E. AU - Sun, J. AU - Savoldo, B. PY - 2011 DA - 2011// TI - Combining mTor inhibitors with rapamycin-resistant T cells: a two-pronged approach to tumor elimination JO - Mol Ther VL - 19 UR - https://doi.org/10.1038/mt.2011.179 DO - 10.1038/mt.2011.179 ID - Huye2011 ER - TY - JOUR AU - Sakashita, K. AU - Kato, I. AU - Daifu, T. AU - Saida, S. AU - Hiramatsu, H. AU - Nishinaka, Y. PY - 2015 DA - 2015// TI - In vitro expansion of CD34+CD38− cells under stimulation with hematopoietic growth factors on AGM-S3 cells in juvenile myelomonocytic leukemia JO - Leukemia VL - 29 UR - https://doi.org/10.1038/leu.2014.239 DO - 10.1038/leu.2014.239 ID - Sakashita2015 ER - TY - JOUR AU - Marin, V. AU - Pizzitola, I. AU - Agostoni, V. AU - Attianese, G. M. AU - Finney, H. AU - Lawson, A. PY - 2010 DA - 2010// TI - Cytokine-induced killer cells for cell therapy of acute myeloid leukemia: improvement of their immune activity by expression of CD33-specific chimeric receptors JO - Haematologica VL - 95 UR - https://doi.org/10.3324/haematol.2010.026310 DO - 10.3324/haematol.2010.026310 ID - Marin2010 ER - TY - JOUR AU - Mardiros, A. AU - Santos, C. AU - McDonald, T. AU - Brown, C. E. AU - Wang, X. AU - Budde, L. E. PY - 2013 DA - 2013// TI - T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia JO - Blood VL - 122 UR - https://doi.org/10.1182/blood-2012-12-474056 DO - 10.1182/blood-2012-12-474056 ID - Mardiros2013 ER - TY - JOUR AU - Pizzitola, I. AU - Anjos-Afonso, F. AU - Rouault-Pierre, K. AU - Lassailly, F. AU - Tettamanti, S. AU - Spinelli, O. PY - 2014 DA - 2014// TI - Chimeric antigen receptors against CD33/CD123 antigens efficiently target primary acute myeloid leukemia cells in vivo JO - Leukemia VL - 28 UR - https://doi.org/10.1038/leu.2014.62 DO - 10.1038/leu.2014.62 ID - Pizzitola2014 ER - TY - JOUR AU - Gill, S. AU - Tasian, S. K. AU - Ruella, M. AU - Shestova, O. AU - Li, Y. AU - Porter, D. L. PY - 2014 DA - 2014// TI - Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor-modified T cells JO - Blood VL - 123 UR - https://doi.org/10.1182/blood-2013-09-529537 DO - 10.1182/blood-2013-09-529537 ID - Gill2014 ER - TY - JOUR AU - Frankel, A. E. AU - Lilly, M. AU - Kreitman, R. AU - Hogge, D. AU - Beran, M. AU - Freedman, M. H. PY - 1998 DA - 1998// TI - Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia JO - Blood VL - 92 ID - Frankel1998 ER - TY - JOUR AU - Matsuda, K. AU - Shimada, A. AU - Yoshida, N. AU - Ogawa, A. AU - Watanabe, A. AU - Yajima, S. PY - 2007 DA - 2007// TI - Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations JO - Blood VL - 109 UR - https://doi.org/10.1182/blood-2006-09-046649 DO - 10.1182/blood-2006-09-046649 ID - Matsuda2007 ER - TY - JOUR AU - Yoshida, N. AU - Yagasaki, H. AU - Xu, Y. AU - Matsuda, K. AU - Yoshimi, A. AU - Takahashi, Y. PY - 2009 DA - 2009// TI - Correlation of clinical features with the mutational status of GM-CSF signaling pathway-related genes in juvenile myelomonocytic leukemia JO - Pediatr Res VL - 65 UR - https://doi.org/10.1203/PDR.0b013e3181961d2a DO - 10.1203/PDR.0b013e3181961d2a ID - Yoshida2009 ER - TY - JOUR AU - Niemeyer, C. M. AU - Kang, M. W. AU - Shin, D. H. AU - Furlan, I. AU - Erlacher, M. AU - Bunin, N. J. PY - 2010 DA - 2010// TI - Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia JO - Nat Genet VL - 42 UR - https://doi.org/10.1038/ng.641 DO - 10.1038/ng.641 ID - Niemeyer2010 ER - TY - JOUR AU - Matsuda, K. AU - Yoshida, N. AU - Miura, S. AU - Nakazawa, Y. AU - Sakashita, K. AU - Hyakuna, N. PY - 2012 DA - 2012// TI - Long-term hematological improvement after non-intensive or no chemotherapy in juvenile myelomonocytic leukemia and poor correlation with adult myelodysplasia spliceosome-related mutations JO - Br J Haematol VL - 157 UR - https://doi.org/10.1111/j.1365-2141.2012.09063.x DO - 10.1111/j.1365-2141.2012.09063.x ID - Matsuda2012 ER - TY - JOUR AU - Hansen, G. AU - Hercus, T. R. AU - McClure, B. J. AU - Stomski, F. C. AU - Dottore, M. AU - Powell, J. PY - 2008 DA - 2008// TI - The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation JO - Cell VL - 134 UR - https://doi.org/10.1016/j.cell.2008.05.053 DO - 10.1016/j.cell.2008.05.053 ID - Hansen2008 ER - TY - JOUR AU - Hercus, T. R. AU - Thomas, D. AU - Guthridge, M. A. AU - Ekert, P. G. AU - King-Scott, J. AU - Parker, M. W. PY - 2009 DA - 2009// TI - The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease JO - Blood VL - 114 UR - https://doi.org/10.1182/blood-2008-12-164004 DO - 10.1182/blood-2008-12-164004 ID - Hercus2009 ER - TY - JOUR AU - Sawai, N. AU - Koike, K. AU - Ito, S. AU - Mwamtemi, H. H. AU - Kurokawa, Y. AU - Kinoshita, T. PY - 1999 DA - 1999// TI - Neutrophilic cell production by combination of stem cell factor and thrombopoietin from CD34+ cord blood cells in long-term serum-deprived liquid culture JO - Blood VL - 93 ID - Sawai1999 ER - TY - JOUR AU - Matsuda, K. AU - Taira, C. AU - Sakashita, K. AU - Saito, S. AU - Tanaka-Yanagisawa, M. AU - Yanagisawa, R. PY - 2010 DA - 2010// TI - Long-term survival after nonintensive chemotherapy in some juvenile myelomonocytic leukemia patients with CBL mutations, and the possible presence of healthy persons with the mutations JO - Blood VL - 115 UR - https://doi.org/10.1182/blood-2009-12-260729 DO - 10.1182/blood-2009-12-260729 ID - Matsuda2010 ER -