None | Healthy T cells | JMML T cellsa | |||
---|---|---|---|---|---|
Mock 1:1 | CAR 1:1 | Mock 1:1 | CAR 1:1 | ||
Patient no. 5 | |||||
CD34+ cells (×104) | 8.85 ± 0.44 | 7.75 ± 0.62 | 2.57 ± 0.33 | 6.73 ± 0.52 | 0.88 ± 0.04 |
CD34+CD38− cells (×104) | 3.78 ± 0.19 | 3.20 ± 0.26 | 0.04 ± 0 | 2.80 ± 0.22 | 0 ± 0 |
CD34+CD38+ cells (×104) | 5.07 ± 0.25 | 4.56 ± 0.37 | 2.53 ± 0.33 | 3.93 ± 0.30 | 0.88 ± 0.04 |
Patient no. 6 | |||||
CD34+ cells (×104) | 9.38 ± 0.77 | 8.15 ± 0.67 | 1.91 ± 0.17* | 7.50 ± 0.49 | 2.50 ± 0.20* |
CD34+CD38− cells (×104) | 5.45 ± 0.45 | 4.65 ± 0.38 | 0.30 ± 0.03* | 4.52 ± 0.30 | 0.55 ± 0.04* |
CD34+CD38+ cells (×104) | 3.93 ± 0.32 | 3.50 ± 0.29 | 1.62 ± 0.15* | 2.98 ± 0.19 | 1.96 ± 0.16* |