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Table 3 Ongoing clinical trials of ASP8273

From: Third-generation inhibitors targeting EGFR T790M mutation in advanced non-small cell lung cancer

Phase

Study population

NCT no.

Phase I

NSCLC patients who have EGFR mutations and received prior treatment with EGFR TKI

02113813

Phase I/II

NSCLC with EGFR mutation and had progressive disease after previous treatment with EGFR TKIs

02192697

Phase II

NSCLC with EGFR mutation and TKI naïve patients

02500927

Phase III

Stage IIIB/IV NSCLC with EGFR mutations

02588261

  1. EGFR: epidermal growth factor receptor, NSCLC: non-small cell lung cancer, TKI: tyrosine kinase inhibitor