Correlation between deletion of the CDKN2 gene and tyrosine kinase inhibitor resistance in adult Philadelphia chromosome-positive acute lymphoblastic leukemia

Table 1 Patient characteristics (N = 135)

Clinical characters	CDKN2 deletion	No CDKN2 deletion	P value
Adults (sample size)	44	91
Male/female	24/20	53/38	0.684
Mean age (years)	33.3 (18–64)	35.4 (18–65)	0.368
WBC count (×10⁹/L)^a	107.7 (1.6~302.0)	69.8 (0.8~353.0)	0.012
Hepatosplenomegaly^a	26 (59.1 %)	31 (34.1 %)	0.006
Complete remission	39 (88.6 %)	85 (93.4 %)	0.337
Stem cell transplantation	34 (77.3 %)	62 (68.1 %)	0.272
Relapse^a	26 (59.1 %)	32 (35.2 %)	0.008

ISSN: 1756-8722