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Table 1 Baseline patient characteristics (N = 21)

From: l-asparaginase-based regimens followed by allogeneic hematopoietic stem cell transplantation improve outcomes in aggressive natural killer cell leukemia

Characteristics

Number of patients

Percentage

Median age, years (range)

50 (16–75)

 

Sex

  

 Male

14

67

 Female

7

33

PS

  

 0–1

12

57

 2–4

9

43

Initial presentation

  

 Fever

20

95

 General weakness

1

5

 DOE

1

5

 Lt. neck swelling

1

5

B symptom (+)

20

95

Hepatomegaly

13

62

Splenomegaly

17

81

Pancytopenia

11

52

LFT abnormality

20

95

DIC

9

43

AKI

4

19

LDH > normal

20

95

Stage IV

21

100

IPI score

  

 Low

1

5

 Low intermediate

7

33

 High intermediate

7

33

 High

6

29

Nodal involvement

7

33

Extranodal involvement

7

33

EBV ISH (+)

17

81

HLH feature

16

76

PET uptake at diagnosis

9

43

  1. PS performance status, DOE dyspnea on exertion, LFT liver function test, DIC disseminated intravascular coagulopathy, AKI acute kidney injury, LDH lactate dehydrogenase, IPI international prognosis index, EBV ISH Epstein-Barr virus in situ hybridization, HLH hemophagocytic lymphohistiocytosis