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Table 1 Baseline patient characteristics (N = 21)

From: l-asparaginase-based regimens followed by allogeneic hematopoietic stem cell transplantation improve outcomes in aggressive natural killer cell leukemia

Characteristics Number of patients Percentage
Median age, years (range) 50 (16–75)  
Sex   
 Male 14 67
 Female 7 33
PS   
 0–1 12 57
 2–4 9 43
Initial presentation   
 Fever 20 95
 General weakness 1 5
 DOE 1 5
 Lt. neck swelling 1 5
B symptom (+) 20 95
Hepatomegaly 13 62
Splenomegaly 17 81
Pancytopenia 11 52
LFT abnormality 20 95
DIC 9 43
AKI 4 19
LDH > normal 20 95
Stage IV 21 100
IPI score   
 Low 1 5
 Low intermediate 7 33
 High intermediate 7 33
 High 6 29
Nodal involvement 7 33
Extranodal involvement 7 33
EBV ISH (+) 17 81
HLH feature 16 76
PET uptake at diagnosis 9 43
  1. PS performance status, DOE dyspnea on exertion, LFT liver function test, DIC disseminated intravascular coagulopathy, AKI acute kidney injury, LDH lactate dehydrogenase, IPI international prognosis index, EBV ISH Epstein-Barr virus in situ hybridization, HLH hemophagocytic lymphohistiocytosis