|
Characteristics
|
Number of patients
|
Percentage
|
|---|
|
Median age, years (range)
|
50 (16–75)
| |
|
Sex
| | |
|
Male
|
14
|
67
|
|
Female
|
7
|
33
|
|
PS
| | |
|
0–1
|
12
|
57
|
|
2–4
|
9
|
43
|
|
Initial presentation
| | |
|
Fever
|
20
|
95
|
|
General weakness
|
1
|
5
|
|
DOE
|
1
|
5
|
|
Lt. neck swelling
|
1
|
5
|
|
B symptom (+)
|
20
|
95
|
|
Hepatomegaly
|
13
|
62
|
|
Splenomegaly
|
17
|
81
|
|
Pancytopenia
|
11
|
52
|
|
LFT abnormality
|
20
|
95
|
|
DIC
|
9
|
43
|
|
AKI
|
4
|
19
|
|
LDH > normal
|
20
|
95
|
|
Stage IV
|
21
|
100
|
|
IPI score
| | |
|
Low
|
1
|
5
|
|
Low intermediate
|
7
|
33
|
|
High intermediate
|
7
|
33
|
|
High
|
6
|
29
|
|
Nodal involvement
|
7
|
33
|
|
Extranodal involvement
|
7
|
33
|
|
EBV ISH (+)
|
17
|
81
|
|
HLH feature
|
16
|
76
|
|
PET uptake at diagnosis
|
9
|
43
|
-
PS performance status, DOE dyspnea on exertion, LFT liver function test, DIC disseminated intravascular coagulopathy, AKI acute kidney injury, LDH lactate dehydrogenase, IPI international prognosis index, EBV ISH Epstein-Barr virus in situ hybridization, HLH hemophagocytic lymphohistiocytosis
