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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: PU.1 controls the expression of long noncoding RNA HOTAIRM1 during granulocytic differentiation

Fig. 2

PU.1 directly binds to the regulatory region of HOTAIRM1. a Genome browser screen shot of the HOTAIRM1 locus. Input (GSM1003475), H3K4me3 (GSM1003536), and H3K27Ac (GSM1003559) ChIP-seq signals of CD14+ monocytes were displayed in the UCSC genome browser. b Schematic representation of putative PU.1 binding sites around the promoter region of HOTAIRM1. c PU.1 ChIP-qPCR showing the enrichment of PU.1 in each putative binding site and the negative site in NB4 or U937 cells upon ATRA treatment for 24 h. The data represent the mean of three replicates ± SD

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