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Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: RETRACTED ARTICLE: Decreased expression of the long noncoding RNA LINC00261 indicate poor prognosis in gastric cancer and suppress gastric cancer metastasis by affecting the epithelial–mesenchymal transition

Fig. 1

Decreased expression of LINC00261 in gastric cancer tissues and cell lines. a LINC00261 expression is analyzed based on GSE13911 database. b Real-time PCR analysis of LINC00261 expression in normal gastric epithelial cell line (GES-1) and gastric cancer cells. Experiments were performed in triplicate. Bars: SD; *P < 0.05, **P < 0.01. c Examined LINC00261 expression by qRT-PCR in 138 paired human gastric cancer tissues and adjacent noncancerous tissues (paired t test, P < 0.001). Data are represented as log2-fold changes (cancer/normal), with “<−1” indicating underexpression and “>1” indicating overexpression. The patients were divided into a low LINC00261 expression group (69) and a high LINC00261 expression group (69), according to the median value of relative LINC00261 expression (3.8-fold, noncancerous/tumors). d, e ROC curves were conducted for prediction of gastric cancer tissues based on GSE13911 database and using qPCR-based LINC00261 expression level. The AUC was 0.921 (d) and 0.812 (e)

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Journal of Hematology & Oncology

ISSN: 1756-8722

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