Table 3 Univariate and multivariate Cox regression analyses LINC00261 for DFS of patients in the study cohort (n = 138)

Univariate analysis

 Age (<50 vs. >50 years)

0.874

0.537–1.424

0.589

 Gender (male vs. female)

0.802

0.484–1.329

0.392

 Location (distal vs. middle + proximal)

0.793

0.487–1.292

0.351

 Tumor size (>5 vs. <5 cm)

1.336

1.041–1.714

0.023*

 Histologic differentiation (well + moderately vs. poorly + undifferentiated)

1.626

0.966–2.738

0.068

 Invasion depth (T1 + T2 vs. T3 + T4)

1.174

0.721–1.911

0.518

 TNM stage (III + IV vs. I + II)

2.620

1.561–4.395

<0.001*

 Lymphatic metastasis (no vs. yes)

0.749

0.583–0.963

0.024*

 Regional lymph nodes (PN2 + PN3 vs. PN0 + PN1)

1.818

1.111–2.972

0.017*

 Distant metastasis (no vs. yes)

0.654

0.482–0.888

0.007*

 Expression of LINC00261 (high vs. low)

0.494

0.300–0.812

0.005*

Multivariate analysis

 TNM stage (III + IV vs. I + II)

1.805

1.090–2.990

0.022*

 Lymphatic metastasis (no vs. yes)

0.887

0.665–1.246

0.125

 Regional lymph nodes (PN2 + PN3 vs. PN0 + PN1)

1.117

0.592–2.111

0.732

 Tumor size (>5 vs. <5 cm)

1.086

0.835–1.433

0.510

 Distant metastasis (no vs. yes)

0.584

0.294–1.162

0.126

 Expression of LINC00261 (high vs. low)

0.551

0.323–0.940

0.029*