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Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: EGFR C797S mutation mediates resistance to third-generation inhibitors in T790M-positive non-small cell lung cancer

Fig. 1

Clonal evolution of NSCLC cancer cells and mechanisms of resistance to third-generation EGFR tyrosine kinase inhibitors. The T790M and C797S mutations were highlighted in the EGFR sequence. Each colored ball represents a distinct clone. The number of balls in each group indicates relative clonal size. NSCLC non-small cell lung cancer, EGFR epidermal growth factor receptor

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