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Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: Lung adenocarcinoma harboring concomitant SPTBN1-ALK fusion, c-Met overexpression, and HER-2 amplification with inherent resistance to crizotinib, chemotherapy, and radiotherapy

Fig. 1

Lung biopsy specimens and total-body PET/CT scan before treatment. Hematoxylin and eosin (H & E) staining (magnification ×200, a), IHC of c-Met (magnification ×200, b), and ALK (magnification ×100, c) of a diagnostic biopsy specimen. Total-body PET/CT showed a 5.1 × 3.7 cm-sized tumor in the right upper lobe (d) with the second lumbar and left ilium metastases (arrowheads, e, f)

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