Fig. 1

Expression of SOCS3 was dysregulated in CML cells. a Expression of endogenous SOCS3 was examined by q-PCR in leukemia cell lines and BMNCs from three healthy donors. β-Actin was served as an internal control. SOCS3 expression in cells from donor 1 was set as a standard. Each point represented the mean of three independent experiments (n = 3).*P < 0.05; compared with standard. b SOCS3 expression in BMNCs from five healthy donors and 15 CML patients was examined by q-PCR. β-Actin was served as an internal control. SOCS3 expression in healthy donor 1 was set as a standard. Each point represented the mean of three independent experiments (n = 3). *P < 0.05; compared with the healthy donor group. All data were expressed as the mean ± SD