Fig. 2

SOCS3 regulated the proliferation and clonogenic growth of CML cells. a Representative pictures showing the effects of SOCS3 over-expression or knock-down on the clonogenic growth of K562 cells. Bar = 50 μm. b Statistical analysis for the number of colonies from CML cells after over-expression of SOCS3 or shRNA vector were transduced into K562 and KU812 cells. Data represented the mean ± SD from three experiments. c The effect of SOCS3 on cell proliferation was examined by the CCK-8 assay. Data represented the mean ± SD from three experiments (n = 3). *P < 0.05; compared with the empty; ^# P < 0.05; compared with shControl