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Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: Heterogeneity of CD34 and CD38 expression in acute B lymphoblastic leukemia cells is reversible and not hierarchically organized

Fig. 1

Subpopulations of adult B-ALL cells reconstituted the leukemia in xenografts. Subpopulations of CD34+CD38, CD34+CD38+, and CD34CD38+ from xenografts of patients #1 and #3 were purified and injected into groups of NSI mice. a Representative FACS analysis of gated hCD45+ BM cells from NSI recipients that were transferred with different subpopulations of engrafted B-ALL cells from patient #1. b Representative FACS analysis of gated hCD45+ BM cells from NSI mice that were transferred with CD34+CD38+ and CD34CD38+ fractions of engrafted B-ALL cells from patient #3

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