Fig. 5

Histological analysis of primary (P0) and passage 1 to 4 (P1-P4) engrafted HGSC. a Dot plots illustrate the success rate of engrafted tumor tissues from P1-P4 (calculated based on the tumor numbers of engraft ones and survival ones). Each dot represents one engraft and number of engrafts listed above (n). b The general patterns of five selected histological parameters in P0 to P4 measured from 8 cases. (c-f) Histologic analysis of four selected parameters (c mitosis; d nuclear and cytoplasmic rate (N/C); e nuclear grade and f stromal %). Available data from four representative cases (OVCA4, 5, 6 and 8) were used for the analysis. At least three engrafts from each case were measured for mean (solid lines) and standard errors (small t-bars)