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Fig. 6 | Journal of Hematology & Oncology

Fig. 6

From: Histologic and molecular analysis of patient derived xenografts of high-grade serous ovarian carcinoma

Fig. 6

Molecular analysis of the selected immunomarkers and global gene profiling in P0 and P2. af Semiquantitative analysis of ER (a), PR (b), HMGA2 (c), KI-67 (d), CD24 (e), and CD133 (f) from four cases. At least three engrafts from each case were measured for mean (solid lines) and standard errors (small t-bars). g Heatmap shows over 130 significantly dysregulated (>twofold) genes between P0 and P2 HGSC. The color red represents overexpressed and blue indicates genes that are under expressed in P2. h The pathway analysis listed the altered functional pathways in P2 tumors in comparison to P0. The length of blue bars indicates the enrichment scores in each pathway

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