Table 2 Correlations between mutational status by NGS analysis and clinical biological parameters

Sex m/f

49/35

72/44

0.594

Age <70/≥70 years

46/38

69/47

0.505

Binet stage a/b/c

66/12/6

95/13/8

0.802

CD38 neg/pos

42/42

79/37

0.010

IGHV mut/unmut

36/48

69/43

0.009

FISH fav/int unfav

48/36

94/22

<0.001

Complex karyotype no/yes

63/19

104/9

0.003