Fig. 1From: NT1014, a novel biguanide, inhibits ovarian cancer growth in vitro and in vivoNT1014 has high affinity for OCT1 and OCT3. Molecular structure of NT1014 (a). HEK293 cells were stably transfected with hOCT1, 2, and 3 (b). Blue color represents nuclei. Affinity for OCT1, OCT2, and OCT3 after treatment of NT1014 or metformin (c). MTT assay were used to assess the growth inhibition by NT1014 and metformin in HEK293 cells transfected with OCT1 and OCT3 (d). *p < 0.05 and **p < 0.01Back to article page