Fig. 6From: Alantolactone selectively ablates acute myeloid leukemia stem and progenitor cellsAlantolactone induced apoptosis by the suppression of NF-kB and its downstream target proteins. The expression of p65, XIAP, FLIP, Bcl-2, Bax, and the cleavage of PARP, caspase-3, caspase-9 was detected by western blot assay after the treatment of alantolactone for 12Â h in primary CD34+ cells, HL60, and KG1a cellsBack to article page