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Table 1 IC50 values (μM) for DpC, Dp44mT, and L1 in MSC, H9C2, MIHA, HK2, and SK-N-LP cells

From: The novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms

 

DpC

Dp44mT

L1

MSC

145.23 ± 13.58

227.32 ± 5.04

>250

H9C2

>250

>250

>250

MIHA

165.73 ± 5.81

227.69 ± 9.93

>250

HK2

17.27 ± 0.19

167.08 ± 0.94

>250

SK-N-LP

<2.5

249.39 ± 51.03

>250

  1. The MSC, H292, MIHA, HK2, and SK-N-LP cells were incubated for 24 h/37 °C with either control, DpC, Dp44mT, or L1 (see “Methods”). The IC50 values (μM) are presented as mean ± standard deviation (n = 3)
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Journal of Hematology & Oncology

ISSN: 1756-8722

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